A victory over Joseph Parker in Cardiff in March saw the unbeaten Briton crowned WBO champion, adding to the WBA and IBF straps he already had in his possession.
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The last time Joshua fought at the national stadium, however, he defeated Wladimir Klitschko in stunning fashion, climbing off the canvas to stop the Ukrainian in the 11th round.
Next up at the venue is Alexander Povetkin, an experienced Russian who has lost only once as a professional. Bigger names may loom large on the horizon, but Joshua will know better than to overlook his challenger.
Ahead of the main event, we look at the vital statistics of both fighters, as well as their career numbers to date.
ANTHONY JOSHUA From: Watford, England Age: 28 Stance: Orthodox Height: 6-6 Weight: 246 lbs. Reach: 82 inches Professional record: 21-0 (20 KOs) KO ratio: 95 percent Major career titles: WBA, WBO and IBF heavyweight titles Last fight: Joseph Parker, March 2018 (Won - points)
